If you have a way of monitoring inlet temp then it may be worth while but I doubt it.

The supercharger is positive displacement pump, giving fixed volume of air per revolution. It produces more air than the motor can consume thus creating postive pressure in the inlet manifold. That is, boost pressure is generally measured in the inlet manifold, so you are measing the backpressure of the supplied air to that which can pass through.

Going larger cams will allow more air to pass through the motor, unless you adjust the cam timing to minimise overlap but you will lose what your trying to gain.

For a turbo motor it is automatically compensated via the wastegate, but for a supercharged motor it simply means less manifold pressure. Cleaner combustion due to additional scavange doubtful to make up for the short fall.

This is a theoretical reason and I am happy to be proven wrong. If you had 256's I'd say go for gold, 264 worth a try, 272 please prove me wrong but I would be monitoring inlet air temp as a measure of how hard the supercharger is working.